Format

Send to

Choose Destination
See comment in PubMed Commons below
AJR Am J Roentgenol. 2013 Mar;200(3):624-9. doi: 10.2214/AJR.12.8679.

ADC values and prognosis of malignant astrocytomas: does lower ADC predict a worse prognosis independent of grade of tumor?--a meta-analysis.

Author information

1
The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institution, 600 N Wolfe St, Phipps B100F, Baltimore, MD 21287, USA.

Abstract

OBJECTIVE:

The purpose of this article is to determine via meta-analysis whether apparent diffusion coefficient (ADC) predicts astrocytoma prognosis independent of grade.

MATERIALS AND METHODS:

Survival data were subjected to Mantel Haenszel analysis in four qualifying studies. Stratification by tumor grade was also performed.

RESULTS:

The survival rates of malignant astrocytomas, grade 3 and 4 (p, 0.004 and < 0.0001, respectively) were worse below a specific ADC value, independent of grade.

CONCLUSION:

Low ADC values correlate with poor survival in malignant astrocytomas independent of tumor grade.

PMID:
23436853
DOI:
10.2214/AJR.12.8679
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center