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Adv Healthc Mater. 2013 Aug;2(8):1114-9. doi: 10.1002/adhm.201200435. Epub 2013 Feb 25.

A self-adjuvanting supramolecular vaccine carrying a folded protein antigen.

Author information

1
Department of Surgery, University of Chicago, 5841 S. Maryland Ave. MC 5032, Chicago, IL 60637 USA; Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Tech M292, Evanston, IL 60208-3109 USA.

Abstract

This work illustrates a strategy for the design of molecularly defined immunotherapies, using a blend of supramolecular peptide self-assembly and active site-directed protein capture.

KEYWORDS:

biomolecular materials; immunotherapy; nanofibers; proteins; self-assembly

PMID:
23436779
PMCID:
PMC3817840
DOI:
10.1002/adhm.201200435
[Indexed for MEDLINE]
Free PMC Article

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