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Am J Surg. 2013 Jul;206(1):47-51. doi: 10.1016/j.amjsurg.2012.10.032. Epub 2013 Feb 20.

Late results after laparoscopic fundoplication denote durable symptomatic relief of gastroesophageal reflux disease.

Author information

1
Southeastern Center for Digestive Disorders & Pancreatic Cancer, Florida Hospital, 3000 Medical Park Drive, Suite 310, Tampa, FL 33613, USA. sharona.ross@yahoo.com

Abstract

BACKGROUND:

Late outcomes after laparoscopic Nissen fundoplication are only now becoming available. This study was undertaken to document late outcomes after laparoscopic Nissen fundoplication.

METHODS:

Five hundred ten patients underwent laparoscopic Nissen fundoplication >10 years ago and were prospectively followed. Preoperatively and postoperatively, patients scored the frequency and severity of symptoms (from 0 = never/not bothersome to 10 = always/very bothersome). Symptom scores before and after fundoplication were compared. Median symptom scores are presented.

RESULTS:

Early after fundoplication, significant improvements were noted in the frequency and severity of symptoms (e.g., for heartburn, from 8 to 0 and from 8 to 0, respectively, P < .001 for each). Late after fundoplication, significant improvements were maintained in the palliation of symptoms (e.g., frequency and severity for heartburn, 2, 1; respectively). At latest follow-up, 89% of patients were pleased with their symptom resolution.

CONCLUSIONS:

With long-term follow-up, laparoscopic Nissen fundoplication durably and significantly palliates symptoms of gastroesophageal reflux disease. This trial promotes the application of laparoscopic Nissen fundoplication.

PMID:
23433888
DOI:
10.1016/j.amjsurg.2012.10.032
[Indexed for MEDLINE]

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