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Case Rep Emerg Med. 2012;2012:942452. doi: 10.1155/2012/942452. Epub 2012 Dec 30.

Antacids, altered mental status, and milk-alkali syndrome.

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Division of Emergency Medicine, Medical University of South Carolina, 169 Ashley Avenue, MSC 300 Room 294, Charleston, SC 29425, USA.


The frequency of milk-alkali syndrome decreased rapidly after the development of histamine-2 antagonists and proton pump inhibitors for the treatment of peptic ulcer disease; however, the availability and overconsumption of antacids and calcium supplements can still place patients at risk (D. P. Beall et al., 2006). Here we describe a patient who presented with altered mental status, hypercalcemia, metabolic alkalosis, and acute renal failure in the context of ingesting large amounts of antacids to control dyspepsia.

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