Format

Send to

Choose Destination
Plant Signal Behav. 2013 May;8(5):e24007. doi: 10.4161/psb.24007. Epub 2013 Feb 21.

L-Cysteine Desulfhydrase 1 modulates the generation of the signaling molecule sulfide in plant cytosol.

Author information

1
Instituto de Bioquímica Vegetal y Fotosíntesis; Consejo Superior de Investigaciones Científicas and Universidad de Sevilla; Sevilla, Spain.

Abstract

Consistent with data in animal systems, experimental evidence highlights sulfide as a signaling molecule of equal importance to NO and H₂O₂ in plant systems. In mammals, two cytosolic enzymes, cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE), have been shown to be responsible for the endogenous production of sulfide. L-cysteine desulfhydrase 1 (DES1) has been recently established as the only enzyme that is involved in the generation of hydrogen sulfide in plant cytosol. Although plants have an available source of sulfide within chloroplasts, the basic stromal pH prevents sulfide release into the cytosol. Therefore, DES1 is essential for the production of sulfide for signaling purposes.

KEYWORDS:

Arabidopsis; autophagy; cysteine; cytosolic sulfide; transcriptional profile

PMID:
23428891
PMCID:
PMC3906162
DOI:
10.4161/psb.24007
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Taylor & Francis Icon for PubMed Central
Loading ...
Support Center