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Int Wound J. 2015 Feb;12(1):53-8. doi: 10.1111/iwj.12050. Epub 2013 Feb 21.

Limb salvage using advanced technologies: a case report.

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Podiatry Department, Carl T. Hayden VA Medical Center, Phoenix VA Health Care System, Phoenix, AZ, USA.


Patients with severe acute and chronic lower extremity wounds often present a significant challenge in terms of limb salvage. In addition to control of infection, assuring adequate perfusion and providing standard wound care, advanced modalities are often required to facilitate final wound closure. We herein present a case study on a diabetic patient with gangrene and necrotising soft-tissue infection who underwent a forefoot pedal amputation to control the sepsis. Despite his non invasive vascular studies demonstrating poor healing potential at this level, he was not deemed suitable for revascularisation by our vascular surgeons and ankle-level amputation was recommended. Nonetheless, over a 5-month period using multiple advanced wound care therapies, wound closure was ultimately achieved.


Advanced wound care therapies; Diabetic foot; Negative pressure wound therapy; Skin substitutes; Wound

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