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Planta Med. 2013 Mar;79(3-4):295-300. doi: 10.1055/s-0032-1328188. Epub 2013 Feb 19.

Chalcones from the flowers of Coreopsis lanceolata and their in vitro antioxidative activity.

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1
Functional Food Center, KIST Gangneung Institute, Gangwon, Korea.

Abstract

Three new chalcones, 3,2'-dihydroxy-4,3'-dimethoxychalcone-4'-glucoside (1), 4'-O-(2'''-O-caffeoyl)2',3',3,4-tetrahydroxychalcone (2), and 2',4',3-trihydroxy-3',4-dimethoxychalcone (3), along with five known phenolics, were isolated from Coreopsis lanceolata flowers. The structures of the new compounds were elucidated by extensive spectroscopic methods including NMR and MS. The three new chalcones showed a good in vitro HepG2 cell protecting effect against tert-butylhydroperoxide-induced oxidative stress.

PMID:
23424011
DOI:
10.1055/s-0032-1328188
[Indexed for MEDLINE]
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