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Environ Toxicol Chem. 2013 Jun;32(6):1426-32. doi: 10.1002/etc.2189. Epub 2013 Apr 19.

Evaluation of phytotoxicity and genotoxicity of nitrobenzene with a battery of Vicia faba assay system.

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  • 1Key Laboratory of Molecular and Cytogenetics, College of Life Sciences and Technology, Harbin Normal University, Heilongjiang Province, China.


Nitrobenzene (NB) is an important organic compound intermediate that is used widely in industry. In the present study, to evaluate the phytotoxicity and genotoxicity of NB on plants, Vicia faba was exposed to increasing concentrations of NB (5 mg L(-1) , 10 mg L(-1) , 25 mg L(-1) , 50 mg L(-1) , and 100 mg L(-1) ). The data revealed that germination rate and radicle length of V. faba seedlings were promoted by low NB concentrations and short exposure periods, whereas these parameters were inhibited at greater NB concentrations and longer exposures. When assessed by mitotic index, micronucleus, and chromosomal aberration assays, NB showed dose-dependent genotoxicity at 0 mg L(-1) to 50 mg L(-1).

Copyright © 2013 SETAC.

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