Format

Send to

Choose Destination
See comment in PubMed Commons below
Pituitary. 2013 Sep;16(3):413-8. doi: 10.1007/s11102-013-0470-8.

Pituitary stem cells: candidates and implications.

Author information

1
Division of Neurosurgery, Department of Surgery, University of Toronto, 30 Bond Street, Toronto, ON, M5B 1W8, Canada. farshad.nassiri@mail.utoronto.ca

Abstract

The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of specialization. Unlike neural stem cells identified in the hippocampus and subventricular zone, pituitary stem cells are not associated with one specific cell type. There are many major candidates that are thought to be potential pituitary stem cell sources. This article reviews the evidence for each of the major cell types and discuss the implications of identifying a definitive pituitary stem cell type.

PMID:
23423660
DOI:
10.1007/s11102-013-0470-8
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Support Center