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Ophthalmic Surg Lasers Imaging Retina. 2013 Mar-Apr;44(2):187-9. doi: 10.3928/23258160-20130212-02. Epub 2013 Feb 19.

Cystoid macular edema secondary to nanoparticle albumin-bound Paclitaxel therapy.

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Jules Stein Eye Institute, University of California, Los Angeles, CA 90095, USA.


The authors report a case of nanoparticle albumin-bound paclitaxel-induced cystoid macular edema (CME) without fluorescein angiographic leakage in a patient being treated for metastatic breast cancer. The CME briskly improved 3 weeks after the chemotherapeutic agent was discontinued and was completely resolved after 6 weeks. Patients receiving taxane therapy must be counseled to report any vision problems during their treatment period because early recognition of this rare but severe adverse event can facilitate appropriate intervention to reverse visual compromise and minimize any potential long-term ophthalmologic sequelae.

[Indexed for MEDLINE]

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