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BMJ Case Rep. 2013 Feb 14;2013. pii: bcr2012007936. doi: 10.1136/bcr-2012-007936.

Relapsing-remitting multiple sclerosis and chronic idiopathic neutropenia: a challenging combination.

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1
Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.

Abstract

We report the challenges of treating relapsing-remitting multiple sclerosis (MS) in a 31-year-old woman with long-standing chronic idiopathic neutropenia. The treatment with the disease-modifying therapy interferon-β was significantly complicated by a further fall in her generally low neutrophil count, to values below 0.5×10(9)/l, although this recovered rapidly when the treatment was stopped. We discuss the difficulties of balancing the risk of neutropenia with a risk of MS relapse.

PMID:
23417376
PMCID:
PMC3604507
DOI:
10.1136/bcr-2012-007936
[Indexed for MEDLINE]
Free PMC Article
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