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Int J Lab Hematol. 2013 Oct;35(5):480-90. doi: 10.1111/ijlh.12054. Epub 2013 Feb 18.

High-throughput on-chip leukemia diagnosis.

Author information

1
Interdisciplinary Program, Bioengineering Major, Graduate School, Seoul National University, Seoul, Korea.

Abstract

Advances in lab-on-a-chip technologies enabled programmable, reconfigurable, and scalable manipulation of a variety of laboratory procedures. Samples, reagents, and fluids can be precisely controlled; buffer temperature, pH, and concentration control systems as well as a variety of detection systems can be integrated on a small chip. These advantages have attracted attention in various fields of clinical application including leukemia diagnosis and research. A lot of research on lab-on-a-chip based diagnosis has been reported and the field is rapidly expanding. This review describes recent developments of lab-on-a-chip technologies as solutions to challenges for high-throughput leukemia diagnosis.

KEYWORDS:

Leukemia; diagnosis; high-throughput screening; lab-on-a-chip; microfluidics

PMID:
23414350
DOI:
10.1111/ijlh.12054
[Indexed for MEDLINE]

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