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Nat Prod Commun. 2012 Dec;7(12):1583-6.

Conversional synthesis of heteratisine.

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1
Department of Chemistry of Medicinal Natural Products, West China College of Pharmacy, Sichuan University, Chengdu, Sichuan, PR China, 610041.

Abstract

The first conversional synthesis of heteratisine has been accomplished in 14 steps and 3.2% overall yield from deltaline, mainly including deoxygenation at C-10, removal of the dioxymethylene moiety, O-demethylation, as well as Baeyer-Villiger oxidation.

PMID:
23413557
[Indexed for MEDLINE]
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