Send to

Choose Destination
See comment in PubMed Commons below
Genomics. 1990 Apr;6(4):685-91.

Structure and chromosomal localization of the human thrombospondin gene.

Author information

Department of Pathology, University of Michigan Medical School, Ann Arbor 48109.


Thrombospondin (THBS1) is a large modular glycoprotein component of the extracellular matrix and contains a variety of distinct domains, including three repeating subunits (types I, II, and III) that share homology to an assortment of other proteins. Determination of THBS1 gene structure has revealed that the type I repeat modules are encoded by symmetrical exons and that the heparin-binding domain is encoded by a single exon. To further elucidate the higher level organization of THBS1, the gene was localized to the q11-qter region of chromosome 15.

[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for MLibrary (Deep Blue)
    Loading ...
    Support Center