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Psychiatry Res. 2013 Oct 30;209(3):737-9. doi: 10.1016/j.psychres.2012.12.016. Epub 2013 Feb 12.

Association of the candidate gene SLC1A1 and obsessive-compulsive disorder in Han Chinese population.

Author information

1
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 200030, Shanghai, China.

Abstract

This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese. The G-A-C-G and G-G-T-C haplotypes were found to be significantly associated with OCD in overall samples, male samples and female samples.

KEYWORDS:

Glutamate transporter gene; Haplotype; Obsessiveā€“compulsive disorder

PMID:
23411042
DOI:
10.1016/j.psychres.2012.12.016
[Indexed for MEDLINE]
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