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J Trop Pediatr. 2013 Jun;59(3):209-13. doi: 10.1093/tropej/fmt003. Epub 2013 Feb 13.

Effect of topical application of chlorhexidine for umbilical cord care in comparison with conventional dry cord care on the risk of neonatal sepsis: a randomized controlled trial.

Author information

1
Department of Pediatrics, Pandit B.D.Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana 124001, India.

Abstract

AIM:

To compare topical application of chlorhexidine for umbilical cord care with conventional dry care for prevention of neonatal sepsis in neonatal intensive care unit (NICU).

METHODS:

The study was conducted in the NICU of a teaching hospital in north India between 2010 and 2011. Newborns (≥ 32 weeks of gestation and weighing ≥ 1500 g) were randomized into chlorhexidine application and dry care groups. Data regarding time of cord separation, umbilical sepsis and neonatal sepsis were recorded.

RESULTS:

One hundred forty (dry care group 70, chlorhexidine group 70) were enrolled and finally analysed. A significant difference was observed among groups in terms of time to cord separation and incidence of blood culture-proven sepsis though there was no statistical difference noted among the groups with regards to umbilical infection, probable sepsis and meningitis.

CONCLUSION:

Use of chlorhexidine for umbilical cord care prevents sepsis in the NICU.

PMID:
23407285
DOI:
10.1093/tropej/fmt003
[Indexed for MEDLINE]

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