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Artif DNA PNA XNA. 2013 Jan-Mar;4(1):1-3. doi: 10.4161/adna.23892. Epub 2013 Jan 1.

Bending of short DNA helices.

Author information

1
Deparment of Chemistry, New York University, New York, NY, USA. alex.vologodskii@nyu.edu

Abstract

In their recent Science paper, Vafabakhsh and Ha claim that DNA duplexes at the range of 100 bp experience anomalous flexibility, much greater than the flexibility of large DNA molecules. ( 1) However, careful reevaluation of their data leads to the conclusion that the presented data do not warrant the authors' claim.

KEYWORDS:

DNA bending flexibility; DNA extreme bendability; DNA minicircles; DNA sticky ends; single-molecule data

PMID:
23406786
PMCID:
PMC3654724
DOI:
10.4161/adna.23892
[Indexed for MEDLINE]
Free PMC Article
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