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Acta Obstet Gynecol Scand. 2013 Jun;92(6):700-5. doi: 10.1111/aogs.12107. Epub 2013 Apr 13.

Induced abortion and breast cancer among parous women: a Danish cohort study.

Author information

1
Section for Epidemiology, Department of Public Health, Health, Aarhus University, Aarhus, Denmark. cmbn@soci.au.dk

Abstract

OBJECTIVE:

We investigated whether induced abortion is associated with breast cancer when lifestyle confounders, including smoking and alcohol consumption, are adjusted for. Design. Prospective cohort study.

SETTING:

Danish women from the Diet, Cancer and Health study.

POPULATION:

A total of 25,576 women.

METHODS:

We obtained exposure data from baseline questionnaires filled in by the women between 1993 and 1997. Information on breast cancer and emigration was retrieved from Danish national registries. The study power was approximately 85% when applying a minimum detection hazard ratio of 1.2.

MAIN OUTCOME MEASURES:

Long-term effects of induced abortion on the risk of breast cancer among women above 50 years of age.

RESULTS:

During a follow up of approximately 12 years, 1215 women were diagnosed with breast cancer. When comparing parous women who had an abortion with parous women who never had an abortion, there was no association between breast cancer risk and induced abortion (ever vs. never), with a hazard ratio 0.95 (95% confidence interval 0.83-1.09), regardless of whether the abortion occurred before the first birth (hazard ratio 0.86; 95% confidence interval 0.65-1.14), or after the first birth (hazard ratio 0.97; 95% confidence interval 0.84-1.13).

CONCLUSIONS:

Our study did not show evidence of an association between induced abortion and breast cancer risk.

PMID:
23402419
DOI:
10.1111/aogs.12107
[Indexed for MEDLINE]

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