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J Autoimmun. 1990 Apr;3 Suppl 1:111-6.

Analysis of T lymphocyte subsets in all stages of diabetes.

Author information

1
Massachusetts General Hospital, Boston.

Abstract

Direct immunofluorescence analysis of circulating blood lymphocytes from patients with all stages of Type I diabetes revealed marked phenotypic abnormalities among all major T-lymphocyte subpopulations. The alterations were most pronounced in the prediabetics and comprised a stimulation of the T4+2H4+ and T8+2H4+ suppressor inducer subpopulations and corresponding depression of the T4+4B4+ helper inducers.

PMID:
2340061
[Indexed for MEDLINE]

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