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Eur J Clin Invest. 2013 Apr;43(4):379-86. doi: 10.1111/eci.12056. Epub 2013 Feb 10.

Physical function measurements predict mortality in ambulatory older men.

Author information

1
Department of Geriatrics, Ghent University Hospital, Ghent, Belgium. Stefanie.Debuyser@UGent.be

Abstract

BACKGROUND:

To assess and compare the predictive value of physical function measurements (PFMs) for all-cause mortality in older men and to evaluate the Timed Up and Go test (TUG) as a predictor in subjects with underlying comorbidity.

DESIGN:

Observational study of a population-based sample of 352 ambulatory older men aged 71-86 at study baseline. The Rapid disability rating scale-2, 36-Item short form health survey, Grip strength, Five times sit-to-stand test, Standing balance, and TUG were determined at baseline. Associations with all-cause mortality were assessed using Cox proportional hazard analyses. Age, Body mass index (BMI), smoking status, education, physical activity and cognitive status were included as confounders. Follow-up exceeded 15 years. Comorbidity status was categorized into cardiovascular disease, chronic obstructive pulmonary disease (COPD) and diabetes mellitus.

RESULTS:

All examined PFMs were associated with all-cause mortality. TUG was the best predictor (adjusted HR per SD increase = 1·58, 95% CI = 1·40-1·79, P < 0·001) for global mortality and continued to be predictive in subjects with cardiovascular disease (adjusted HR per SD increase = 1·80, 95% CI = 1·40-2·33, P < 0·001).

CONCLUSIONS:

The assessment of physical functioning is important in the evaluation of older persons. We encourage the use of the TUG as a reliable, quick and feasible screening tool in clinical settings.

PMID:
23398295
DOI:
10.1111/eci.12056
[Indexed for MEDLINE]

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