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Cell Metab. 2013 Feb 5;17(2):155-6. doi: 10.1016/j.cmet.2013.01.008.

How sugar tunes your clock.

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1
Department of Biological Chemistry, Johns Hopkins University, School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205-2185, USA. gwhart@jhmi.edu

Abstract

While cellular circadian clocks are set by the light/dark cycle, these clocks can be reset by what we eat. Two papers in this issue of Cell Metabolism reveal that O-GlcNAcylation of clock proteins, which is dependent on nutrients, adjusts our circadian clock (Kaasik et al., 2013; Li et al., 2013).

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