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Biosci Biotechnol Biochem. 2013;77(2):392-4. Epub 2013 Feb 7.

Natto (fermented soybean) extract extends the adult lifespan of Caenorhabditis elegans.

Author information

1
Oyamatofu Co., Ltd., Shirone, Isehara, Kanagawa, Japan. sachie_i@tg7.co-net.ne.jp

Abstract

We investigated the effects of a water extract of natto on the aging of the nematode Caenorhabditis elegans. The water extract significantly prolonged the adult lifespan of the wild-type worms and rendered them resistant to oxidative and thermal stress. In addition, treatment with natto extract significantly delayed the accumulation of lipofuscin, a characteristic of aging cells. Our findings suggest that components of natto have a beneficial anti-aging effect in vivo.

PMID:
23391920
DOI:
10.1271/bbb.120726
[Indexed for MEDLINE]
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