Send to

Choose Destination
See comment in PubMed Commons below
J Chem Phys. 2013 Jan 28;138(4):044903. doi: 10.1063/1.4789019.

Simulation on the translocation of polymer through compound channels.

Author information

Department of Physics, Zhejiang University, Hangzhou 310027, China.


The translocation of a polymer through compound channels under external electrical field was investigated by Monte Carlo simulation on a three-dimensional simple cubic lattice. The compound channel is composed of two parts: part α with length L(pα) and part β with length L(pβ). The two parts have different polymer-channel interactions: a strong attractive interaction with strength ε(α) for part α and a variable interaction with strength ε(β) for part β. Results show that the translocation process is remarkably affected by both ε(β) and L(pα), and the fastest translocation can be achieved with a proper choice of ε(β) and L(pα). When ε(β) is large, the translocation is dominated by the last escaping process as it is difficult for the polymer chain to leave the channel. Whereas when L(pα) is small and ε(β) ≪ ε(α), the translocation is determined by the initial filling process. For this case, there is a free-energy well at the interface between the part α and the part β, which not only influences the filling dynamics but also affects the translocation probability.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Institute of Physics
    Loading ...
    Support Center