Send to

Choose Destination
See comment in PubMed Commons below
Yao Xue Xue Bao. 2012 Nov;47(11):1521-6.

[Identification of metabolites of arbidol by ultra-high performance liquid chromatography tandem mass spectrometry].

[Article in Chinese]

Author information

College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210046, China.


UPLC-MS-MS system was used for the identification of arbidol metabolites in the rat feces, urine and plasma samples. The system was so powerful a way with high ability of separation and analysis, based on both chromatography and mass properties. The isotope of Br was also a good indicator for metabolites finding. There were altogether 9 metabolites detected and identified, including 2 phase I biotransformation products and 7 phase II ones. It is concluded that arbidol mainly undergo metabolic reactions such as N-demethylation, S-oxidation, glucuronidation and sulfation in rats.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center