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Elife. 2013 Jan 29;2:e00563. doi: 10.7554/eLife.00563.

Bacteria herald a new era of gene editing.

Author information

1
is at the Genome Center and the Department of Biochemistry and Molecular Medicine , University of California, Davis , United States djsegal@ucdavis.edu.

Abstract

The demonstration that nucleases guided by bacterial RNA can disrupt human genes represents a landmark in the rapidly developing field of genome engineering.

KEYWORDS:

Cas9; Human; endonuclease; genome editing

PMID:
23386979
PMCID:
PMC3557904
DOI:
10.7554/eLife.00563
[Indexed for MEDLINE]
Free PMC Article
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