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J Cosmet Laser Ther. 2013 Aug;15(4):200-6. doi: 10.3109/14764172.2012.761346. Epub 2013 Feb 5.

A retrospective study of the management of Chinese melasma patients using a 1927 nm fractional thulium fiber laser.

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Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.



A new fractional photothermolysis device is used in our retrospective study to treat melasma in Chinese patients.


To evaluate the efficacy and safety of the 1927 nm fractional thulium fiber laser in the treatment of melasma in Chinese patients.


Eleven melasma patients who received treatment between November 2009 and May 2010 were included. Photographic images at baseline and follow-up were assessed for clinical efficacy and complications by two independent and blinded physicians. Questionnaires were also completed by patients.


Significant MASI improvements were seen at 1 week, 1 month and 2 months, but not at 3 months. Patients' degree of satisfaction was high. Significant improvement in skin texture and pore size was seen for up to 2 months and improvement in wrinkles for up to a month. There was no change in skin laxity. Main adverse effects seen were erythema, edema, and crusting in the early days. One patient developed PIH.


The novel 1927 nm fractional thulium fiber laser is safe and effective in the management of melasma in Chinese patients for up to 2 months. It is also useful in photo-rejuvenation. Complications were limited to erythema and edema in the early days, and transient PIH.

[Indexed for MEDLINE]

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