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Catheter Cardiovasc Interv. 2013 Oct 1;82(4):E465-8. doi: 10.1002/ccd.24853. Epub 2013 Apr 8.

Type II complex regional pain syndrome of the hand resulting from repeated arterial punctures during transradial coronary intervention.

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Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.


Coronary catheterization using a transradial approach has become a common procedure, as the risks of local complications are low and this procedure affords relatively expeditious postprocedural patient mobilization. Access site complications--such as radial artery spasm, hematoma, and compartment syndrome--have been reported in the literature; however, cases of complex regional pain syndrome (CRPS) of the hand related to the procedure are extremely rare. We describe a case of type II CRPS affecting the hand after a transradial coronary intervention that was complicated by repeated periprocedural arterial punctures. In this case, a 55-year-old woman underwent a percutaneous coronary intervention for the treatment of unstable angina. After successful completion of the procedure, the patient complained of severe pain along the median and radial nerve distributions and resulting disability of the right hand. Although subsequent duplex sonography showed no abnormalities, a nerve conduction study uncovered injury to multiple nerves on the right. A diagnosis of type II CRPS was then made and the patient was treated with a nerve block as well as multiple medical modalities. This case demonstrates a very unusual complication resulting from the transradial approach to percutaneous coronary intervention.


complex regional pain syndrome type II; coronary catheterization; transradial approach

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