Format

Send to

Choose Destination
See comment in PubMed Commons below
Schizophr Res. 2013 Mar;144(1-3):146-50. doi: 10.1016/j.schres.2012.12.012. Epub 2013 Feb 1.

Functional outcomes, functional capacity, and cognitive impairment in schizotypal personality disorder.

Author information

1
Department of Psychiatry, Mt. Sinai School of Medicine, New York, NY, United States. Margaret.McNamara@mssm.edu

Abstract

BACKGROUND:

Individuals with schizotypal personality disorder (SPD) exhibit impaired cognitive functioning in a pattern similar to that found in schizophrenia; less clear is the extent to which these individuals also share schizophrenia patients' impairments in functional capacity and real-world functioning.

METHOD:

We evaluated 46 SPD patients, as well as 38 individuals with avoidant personality disorder (AvPD) and 55 healthy controls (HC) on: cognitive functioning, real-world functioning (employment and residential status), and functional capacity (indexed by the UPSA, a performance-based skills assessment).

RESULTS:

We found that individuals with SPD exhibited worse performance on both the cognitive battery and the UPSA than the other groups; they were also less likely to be employed and to be living independently. Additionally, cognitive and UPSA performance in the SPD group was intercorrelated to a degree comparable to what has been found in schizophrenia, and this relationship was not present in the AvPD group. Finally, real-world functioning was related to UPSA performance for both patient groups.

CONCLUSIONS:

SPD patients exhibit impaired real-world functioning suggesting that these deficits extend across the schizophrenia spectrum. In addition, there is supportive evidence for the validity and importance of performance-based measures such as the UPSA to predict everyday outcomes across the schizophrenia spectrum.

PMID:
23375943
PMCID:
PMC3572293
DOI:
10.1016/j.schres.2012.12.012
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center