Format

Send to

Choose Destination
Biochemistry. 2013 Mar 26;52(12):2068-77. doi: 10.1021/bi301504m. Epub 2013 Feb 12.

Importance of protein dynamics during enzymatic C-H bond cleavage catalysis.

Author information

1
Department of Chemistry, Department of Molecular and Cell Biology, and California Institute for Quantitative Biosciences (QB3), University of California , Berkeley, California 94720-3220, United States.

Abstract

Quantum tunneling and protein dynamics have emerged as important components of enzyme function. This review focuses on soybean lipoxygenase-1, to illustrate how the properties of enzymatic C-H bond activation link protein motions to the fundamental bond making-breaking processes.

PMID:
23373460
PMCID:
PMC4091948
DOI:
10.1021/bi301504m
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for American Chemical Society Icon for PubMed Central
Loading ...
Support Center