Format

Send to

Choose Destination
Orthopade. 2013 Feb;42(2):125-39. doi: 10.1007/s00132-012-2016-6.

[Conservative therapy of osteoarthritis].

[Article in German]

Author information

1
Orthopädische Klinik und Poliklinik, Universitätsmedizin Rostock, Rostock, Deutschland. info@oz-mo.de

Abstract

Osteoarthritis of the knee is a degenerative joint disease with progressive degradation of articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking and joint effusion depending on the stage of the disease. In an effort to delay major surgery, patients with knee osteoarthritis are offered a variety of nonsurgical modalities, such as weight loss, exercise, physiotherapy, bracing, orthoses, nonsteroidal anti-inflammatory drugs (NSAIDs) and intra-articular viscosupplementation or corticosteroid injection. In general, the goals of these therapeutic options are to decrease pain and improve function. Some of these modalities may also have a disease-modifying effect by altering the mechanical environment of the knee. Chondroprotective substances, such as lucosamine, chondroitin sulphate and hyaluronic acid are safe and provide short-term symptomatic relief while the therapeutic effects remain uncertain.

PMID:
23370727
DOI:
10.1007/s00132-012-2016-6
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center