Format

Send to

Choose Destination
See comment in PubMed Commons below
Langmuir. 2013 Feb 19;29(7):2094-8. doi: 10.1021/la3044126. Epub 2013 Feb 6.

pH control of the electrostatic binding of gold and iron oxide nanoparticles to tobacco mosaic virus.

Author information

1
CIC nanoGUNE Consolider, Donostia-San Sebastián, Spain.

Abstract

We report the binding of nanoparticles (NPs) to wild type (unmodified) tobacco mosaic virus (TMV). The viruses are simply mixed with citrate-coated, negatively charged gold and iron oxide nanoparticles (IONPs) in acidic solution. This results in TMV decorated along its whole length by the respective particles. Such a decoration usually requires chemical modification or mutation of TMV (e.g., cysteine residues), but here we simply reduce TMV's natural negative charge by protonation. The particles are protonated to a much smaller extent. This charge-based mechanism does not operate for neutral particles.

PMID:
23368877
DOI:
10.1021/la3044126
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center