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Conf Proc IEEE Eng Med Biol Soc. 2012;2012:2056-9. doi: 10.1109/EMBC.2012.6346363.

Experimental glucose regulation with a high-order sliding-mode controller.

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1
Unidad de Investigación en Enfermedades Metabólicas, Centro Médico Nacional Siglo XXI (IMSS), México. anagabygh@gmail.com

Abstract

Theoretically High-Order Sliding-Mode Controllers are well suited to perform closed loop glucose regulation because they are insensitive to parameter uncertainties and robust to unknown dynamics that may perturb the system. The implementation of the controller based on the concept of practical relative degree is presented. The controller was tested in Sprague-Dawley rats with steptozotocin induced diabetes. The tests demonstrated high efficacy and robustness of the controller.

PMID:
23366324
DOI:
10.1109/EMBC.2012.6346363
[Indexed for MEDLINE]
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