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Conf Proc IEEE Eng Med Biol Soc. 2012;2012:539-42. doi: 10.1109/EMBC.2012.6345987.

A S-parameters-based detection method for a multilayer SPR biosensor.

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  • 1School of Engineering, Deakin University, Geelong, Victoria 3217, Australia.


In this paper, S-parameters investigation of a variable incidence angle multilayer SPR biosensor is presented. Both magnitude and phase of the S-parameters are taken into account in the investigation. The work presented in this paper is the first attempt to apply S-parameters analysis to a multilayer SPR biosensor. The goal is to improve sensitivity through involving S-parameters including their phase values. In addition, further investigation is carried out to understand the relationship between the S-parameters and thickness of biomolecular layer and also the design parameters including the number of graphene layers.

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