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Exerc Sport Sci Rev. 2013 Apr;41(2):116-22. doi: 10.1097/JES.0b013e3182877deb.

Exercise and hematopoietic stem and progenitor cells: protection, quantity, and function.

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1
Department of Kinesiology, McMaster University, Hamilton, Canada.

Abstract

The effects of exercise on mature cells of the hematopoietic lineage have been well characterized; however, the effects of exercise on the more primitive cells of the hematopoietic system are unknown. Here, we propose that the benefits of exercise apply to hematopoietic progenitors and that exercise increases hematopoietic stem cell quantity primarily mediated via adaptations in the stem cell niche.

PMID:
23364348
DOI:
10.1097/JES.0b013e3182877deb
[Indexed for MEDLINE]
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