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Methods Mol Biol. 2013;980:131-56. doi: 10.1007/978-1-62703-287-2_7.

DNA methylation analysis in human cancer.

Author information

1
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Abstract

The functional impact of aberrant DNA methylation and the widespread alterations in DNA methylation in cancer development have led to the development of a variety of methods to characterize the DNA methylation patterns. This chapter critiques and describes the major approaches to analyzing DNA methylation.

PMID:
23359152
PMCID:
PMC3888804
DOI:
10.1007/978-1-62703-287-2_7
[Indexed for MEDLINE]
Free PMC Article

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