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Nat Genet. 2013 Feb;45(2):121-2. doi: 10.1038/ng.2540.

The burden of faulty proofreading in colon cancer.

Author information

1
Genentech Inc., Department of Molecular Biology, South San Francisco, California, USA. sekar@gene.com

Erratum in

  • Nat Genet. 2013 Oct;45(10):1261.

Abstract

Our understanding of inherited risk factors for colorectal cancer (CRC) is incomplete. A new study reports the identification of germline CRC risk variants that adversely affect the proofreading function of DNA polymerases encoded by POLE and POLD1.

PMID:
23358219
DOI:
10.1038/ng.2540
[Indexed for MEDLINE]

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