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Epilepsy Behav. 2013 Apr;27(1):22-8. doi: 10.1016/j.yebeh.2012.12.009. Epub 2013 Jan 28.

Texture analysis of magnetic resonance images of patients with juvenile myoclonic epilepsy.

Author information

  • 1Neurophysics Group, State University of Campinas, Brazil. marciaso@ifi.unicamp.br

Erratum in

  • Epilepsy Behav. 2013 Jun;27(3):515.

Abstract

BACKGROUND/PURPOSE:

Juvenile myoclonic epilepsy (JME) is the most frequent subsyndrome of the idiopathic generalized epilepsies, and experimental investigations support that the thalamus is a key structure in the mechanisms of JME. Texture analysis (TA) is an image processing technique which can be used to characterize images such as MRI.

OBJECTIVE:

The goal of this work was to investigate the thalamus of patients with JME using TA, a quantitative neuroimaging technique.

METHODS:

Patients and controls were submitted to MRI investigation. Images were acquired in a 2-Tesla scanner. The T1 volumetric sequence was used for thalamic segmentation and extraction of texture parameters. Twenty-four patients with a diagnosis of JME and 20 healthy volunteers were investigated.

RESULTS:

Texture analysis revealed differences between the right thalamus of patients and controls.

CONCLUSIONS:

The present investigation supports the participation of the thalamus in the disease mechanisms of JME. Texture analysis may be a useful tool in the quantitative neuroimaging investigation of the epilepsies and can be important to understand JME.

PMID:
23357730
DOI:
10.1016/j.yebeh.2012.12.009
[PubMed - indexed for MEDLINE]
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