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Hemodial Int. 2013 Oct;17(4):652-5. doi: 10.1111/hdi.12020. Epub 2013 Jan 24.

Case report: atenolol overdose successfully treated with hemodialysis.

Author information

1
Department of Medicine, London Health Sciences Centre, Nephrology Division, Western University, London, Canada.

Abstract

Owing to the drug's favorable hydrophilic and pharmacokinetic characteristics, a number of case reports have demonstrated effective treatment of atenolol overdose with hemodialysis. However, the efficiency of atenolol clearance throughout hemodialysis treatments has not previously been examined. In this report, a patient with impaired renal function was successfully treated with two 5-hour intermittent high-flux high-efficiency hemodialysis therapies after atenolol overdose. Serial atenolol levels were measured during his hemodialysis treatments. We observed an over 50% plasma atenolol concentration reduction after each 5-hour hemodialysis therapy. Hemodialysis therapy is an effective treatment for atenolol overdose, especially in patients with impaired renal function.

KEYWORDS:

Hemodialysis; atenolol; drug intoxication; overdose

PMID:
23347063
DOI:
10.1111/hdi.12020
[Indexed for MEDLINE]

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