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Case Rep Hematol. 2013;2013:563291. doi: 10.1155/2013/563291. Epub 2013 Jan 3.

t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature.

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1
Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN 37232, USA.

Abstract

Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. There are several case reports in the literature describing t(17;19) in children with ALL. This translocation has been associated with hypercalcemia, coagulopathy, and poor outcome. We present three cases of ALL with t(17;19) treated at our institution and review the outcome of children reported in the medical literature.

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