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Sci Transl Med. 2013 Jan 23;5(169):169fs2. doi: 10.1126/scitranslmed.3005424.

A splicing twist on metastasis.

Author information

1
Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

Abstract

An oncogenic splice variant of the transcription factor KLF6 is associated with metastasis and poor survival in node-negative breast cancer patients and promotes the epithelial-to-mesenchymal transition by regulating Twist.

PMID:
23345607
DOI:
10.1126/scitranslmed.3005424
[Indexed for MEDLINE]

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