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Cell Host Microbe. 2013 Jan 16;13(1):8-14. doi: 10.1016/j.chom.2012.12.004. Epub 2013 Jan 16.

Host-intestinal microbiota mutualism: "learning on the fly".

Author information

1
Institut de Génomique Fonctionnelle de Lyon (IGFL), Ecole Normale Supérieure de Lyon, CNRS UMR 5242, Université Claude Bernard Lyon 1, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.

Abstract

Given the complexity of the mammalian microbiota, there is a need for simple models to decipher the effector and regulatory mechanisms underlying host/microbiota mutualism. Approaches using Drosophila and its simple microbiota carry the potential to unravel the evolutionarily conserved mechanisms engaged in this association. Here, we review recent work carried out in this model, providing insights and exciting perspectives.

PMID:
23332152
DOI:
10.1016/j.chom.2012.12.004
[Indexed for MEDLINE]
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