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Nat Rev Rheumatol. 2013 Feb;9(2):74-6. doi: 10.1038/nrrheum.2012.235. Epub 2013 Jan 15.

Regenerative medicine in 2012: the coming of age of musculoskeletal tissue engineering.

Author information

1
Department of Orthopaedic Surgery, Center for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine, 450 Technology Drive, Room 221, Pittsburgh, PA 15219, USA. rst13@pitt.edu

Abstract

Tissue engineering and regenerative medicine have advanced rapidly towards the development of therapeutic solutions for musculoskeletal disorders. In 2012, breakthroughs have been made in the guidance of adult stem cell homing, the tissue regenerative activity of stem-cell-derived extracellular matrix has been tested, and novel, mechanically superior biomaterials have been fabricated.

PMID:
23321611
PMCID:
PMC4877685
DOI:
10.1038/nrrheum.2012.235
[Indexed for MEDLINE]
Free PMC Article
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