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Case Rep Rheumatol. 2012;2012:724013. doi: 10.1155/2012/724013. Epub 2012 Dec 23.

Pulmonary Sarcoidosis following Etanercept Treatment.

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Department of Rheumatology, Wycombe General Hospital, Queen Alexander Road, Wycome, Buckinghamshire HP11 2TT, UK.


Tumour necrosis factor (TNF) is an important cytokine involved in the pathology of a number of inflammatory conditions, and thus blockade with anti-TNF therapies is becoming the cornerstone in managing such diseases. With increasing use, evidence is collected for the association of sarcoid-like granulomatous disease developing after the initiation of anti-TNF-α therapy, with disease reversal after discontinuation.

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