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Cancer Genet Cytogenet. 1990 May;46(1):75-81.

Cytogenetics of carcinoma in situ of the testis.

Author information

1
Department of Medical Genetics, State University of Groningen, The Netherlands.

Abstract

Carcinoma in situ (CIS) of the testis is the precursor lesion of most testicular germ cell tumors (TGCTs). Karyotyping of CIS is important for a better understanding of the pathogenesis of TGCTs and the progression to invasive cancer. We karyotyped three cases of CIS. All three cases showed a numerical abnormal chromosomal pattern. In one case, two copies of the germ cell tumor marker i(12p) were found.

PMID:
2331686
DOI:
10.1016/0165-4608(90)90011-x
[Indexed for MEDLINE]

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