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J Am Heart Assoc. 2012 Oct;1(5):e004085. doi: 10.1161/JAHA.112.004085. Epub 2012 Oct 25.

Very long-term (15 to 23 years) outcomes of successful balloon angioplasty compared with bare metal coronary stenting.

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1
Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.

Abstract

BACKGROUND:

Target lesion revascularization (TLR) continues to occur beyond 4 years after bare metal stent (BMS) implantation. However, long-term outcomes after balloon angioplasty (BA) compared with BMS are currently unknown.

METHODS AND RESULTS:

From 1989 to 1990, 659 patients (748 lesions) underwent successful BA with final balloon ≥3.0 mm excluding patients with acute myocardial infarction and were compared with 405 patients (424 lesions) with BMS implantation from June 1990 to 1993. Cumulative incidences of death and target lesion thrombosis (>1 year) were similar between the BA group and the BMS group (44.4% versus 45.4%, P=0.60; and 1.5% versus 0.7%, P=0.99; respectively). Cumulative incidence of TLR during overall follow-up was significantly higher after BA than after BMS implantation (44.6% versus 36.0%, P<0.001), whereas cumulative incidence of late TLR (>4 years) tended to be lower in the BA group than in the BMS group (16.3% versus 21.4%, P=0.16). Cumulative incidence of late TLR after BA was significantly lower in patients with small percent diameter stenosis (%DS) at early follow-up angiography compared with large %DS (14.5% versus 28.0%, P=0.02). In lesions with serial angiography, late lumen loss from early (6 to 14 months) to long-term (4 to 10 years) follow-up angiography was significantly smaller in the BA group (n=42) than in the BMS group (n=55) (-0.08±0.45 mm versus 0.11±0.46 mm, P=0.047).

CONCLUSIONS:

Compared with BMS implantation, BA was associated with a trend for less late TLR beyond 4 years and with significantly smaller late lumen loss from early to long-term follow-up angiography.

KEYWORDS:

bare metal stent; coronary artery disease; late restenosis; percutaneous transluminal coronary angioplasty; prognosis

PMID:
23316303
PMCID:
PMC3541619
DOI:
10.1161/JAHA.112.004085
[Indexed for MEDLINE]
Free PMC Article
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