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Clin Appl Thromb Hemost. 2014 May;20(4):427-32. doi: 10.1177/1076029612473516. Epub 2013 Jan 11.

Predictive value of elevated neutrophil to lymphocyte ratio in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction.

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1
1Department of Cardiology, Bezmialem Vakıf University, School of Medicine, Istanbul, Turkey.

Abstract

OBJECTIVES:

The neutrophil to lymphocyte ratio (NLR) has been investigated as a new predictor for cardiovascular risk. Admission NLR would be predictive of adverse outcomes after primary angioplasty for ST-segment elevation myocardial infarction (STEMI).

METHODS:

A total of 2410 patients with STEMI undergoing primary angioplasty were retrospectively enrolled. The study population was divided into tertiles based on the NLR values. A high NLR (n = 803) was defined as a value in the third tertile (>6.97), and a low NLR (n = 1607) was defined as a value in the lower 2 tertiles (≤6.97).

RESULTS:

High NLR group had higher incidence of inhospital and long-term cardiovascular mortality (5% vs 1.4%, P < .001; 7% vs 4.8%, P = .02, respectively). High NLR (>6.97) was found as an independent predictor of inhospital cardiovascular mortality (odds ratio: 2.8, 95% confidence interval: 1.37-5.74, P = .005).

CONCLUSIONS:

High NLR level is associated with increased inhospital and long-term cardiovascular mortality in patients with STEMI undergoing primary angioplasty.

KEYWORDS:

ST-segment elevation myocardial infarction; lymphocytes; neutrophils; primary angioplasty

PMID:
23314674
DOI:
10.1177/1076029612473516
[Indexed for MEDLINE]
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