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J Natl Compr Canc Netw. 2013 Jan 1;11(1):78-98.

Small cell lung cancer.

Abstract

Neuroendocrine tumors account for approximately 20% of lung cancers; most (≈15%) are small cell lung cancer (SCLC). These NCCN Clinical Practice Guidelines in Oncology for SCLC focus on extensive-stage SCLC because it occurs more frequently than limited-stage disease. SCLC is highly sensitive to initial therapy; however, most patients eventually die of recurrent disease. In patients with extensive-stage disease, chemotherapy alone can palliate symptoms and prolong survival in most patients; however, long-term survival is rare. Most cases of SCLC are attributable to cigarette smoking; therefore, smoking cessation should be strongly promoted.

PMID:
23307984
PMCID:
PMC3715060
DOI:
10.6004/jnccn.2013.0011
[Indexed for MEDLINE]
Free PMC Article

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