Format

Send to

Choose Destination
See comment in PubMed Commons below
Lab Chip. 2013 Feb 21;13(4):602-9. doi: 10.1039/c2lc90148j.

Probing circulating tumor cells in microfluidics.

Author information

1
Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.

Abstract

Circulating tumor cells (CTCs) are important targets for study as we strive to better understand, diagnose, and treat cancers. However, CTCs are found in blood at extremely low concentrations; this makes isolation, enrichment, and characterization of CTCs technically challenging. Recently, the development of CTC separation devices has grown rapidly in both academia and industry. Part of this development effort centered on microfluidic platforms, exploiting the advantages of microfluidics to improve CTC separation performance and device integration. In this Focus article, we highlight some of the recent work in microfluidic CTC separation and detection systems and discuss our appraisal of what the field should do next.

PMID:
23306378
PMCID:
PMC3990734
DOI:
10.1039/c2lc90148j
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry Icon for PubMed Central
    Loading ...
    Support Center