Format

Send to

Choose Destination
See comment in PubMed Commons below
J Org Chem. 2013 Feb 1;78(3):1230-5. doi: 10.1021/jo302404v. Epub 2013 Jan 22.

Stereoselective synthesis of fused spiroindolines via tandem Mannich/intramolecular aminal formation.

Author information

1
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, People's Republic of China.

Abstract

A novel tandem Mannich/intramolecular aminal formation between tryptamines and salicylaldehydes was reported. This strategy provides a promising approach for the stereoselective synthesis of a range of complex fused spiroindolines, which bear a highly congested contiguous spiro quaternary center and two tertiary stereocenters, in a highly economical and effective fashion.

PMID:
23305299
DOI:
10.1021/jo302404v
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center