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Analyst. 2013 Feb 21;138(4):1015-9. doi: 10.1039/c2an36274k.

A facile and cost-effective TEM grid approach to design gold nano-structured substrates for high throughput plasmonic sensitive detection of biomolecules.

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1
Laboratoire de Nanotechnologie et d'Instrumentation Optique, Institute Charles Delaunay, Université de Technologie de Troyes, UMR-STMR CNRS 6279, 12 Rue Marie Curie CS 42060, 10004 Troyes, France.

Abstract

A commercial TEM grid was used as a mask for the creation of extremely well-organized gold micro-/nano-structures on a glass substrate via a high temperature annealing process at 500 °C. The structured substrate was (bio)functionalized and used for the high throughput LSPR immunosensing of different concentrations of a model protein named bovine serum albumin.

PMID:
23304693
DOI:
10.1039/c2an36274k
[Indexed for MEDLINE]
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